ECLA today represents a new form of liberal education, but the original efforts to create a liberal arts college in Berlin are still part of ECLA’s overall goals: to create a residential college for students from all over the world, to teach in English, to rely on small-group, interactive teaching formats like tutorials and seminars, and to create a first-rate liberal arts education relevant for the 21st century.

The original ECLA was founded in 1999 as a non-profit association (gemeinnützige Verein) by German intellectuals and entrepreneurs interested in liberal education. With first-hand experience from some of the best colleges in the U.S. and U.K., and inspired by the European and American liberal arts tradition, the first step of the Verein was to create a summer school. Under the leadership of Stefan Gutzeit, who had studied at Stanford and Harvard, ECLA's first International Summer University was held with great success in 2000 at the Hufeland Campus in Berlin-Buch. That success continued in 2001 and 2002.

The academic year of 2002-3 was very significant for ECLA's development. The college became a non-profit organization (gGmbh), changed management, and introduced its first one-year programme. Under the leadership of Erika Anita Kiss, who brought experience from Harvard and Oxford to the project, ECLA introduced the Foundation Year Programme (which later became the Academy Year Programme). Following extensive interviews in Berlin, Oxford and New York, seven new faculty members were recruited to develop and teach a year-long, problem-centred liberal arts curriculum dominated by philosophy, literature, political theory and visual arts. From the beginning the programme tended to attract bright and broadminded students, ready not just for intensive reading and writing, but also for reflection on the meaning of liberal education. Ongoing discussions among faculty and students about the nature and significance of liberal education have been an essential part of the ECLA culture since then.

In 2003, ECLA's organizational structure changed again, and the institution began to assume the shape it has today. The Endeavor Foundation, led by Julie J. Kidd, was already a major sponsor for ECLA’s first full-year programme. The Endeavor Foundation now secured the long term financial stability of ECLA, and decided to support the project with relevant expertise at every step of its development. In New York, a Board of Trustees was formed. Later on, a Council of Advisors was created. In Berlin, Peter Hajnal and Thomas Nørgaard (who had joined the ECLA faculty the year before from Columbia University and Oxford University, respectively) became Programme Directors responsible for curricular development and the introduction of a new one-year programme that continues today as the Project Year.

In 2003-4, ECLA moved to its present campus in Berlin Niederschönhausen, with Richard Shriver acting as ECLA's Provost and Managing Director (2002-2005). Shriver, who is now Provost Emeritus, brought invaluable business experience to the project and played a crucial role in the acquisition and renovation of several buildings for creating ECLA's campus and its services, as well as the basic organizational structure. From 2004-7, Laurent Boetsch served as ECLA's President. Boetsch, who is now President Emeritus, brought expertise from American college administration to the project, helped ECLA with the first stage of the accreditation process, and contributed in important ways to ECLA’s recruitment efforts and partnership initiatives.  Since 2007, Peter Hajnal and Thomas Nørgaard have served as Co-Deans of the College and of Academic Affairs. They have led the joint faculty work on a new 'value questions' approach to liberal education, and on the BA in Value Studies.

In 2009, ECLA will celebrate both the 10th International Summer University and the introduction of the new BA in Value Studies. The faculty is growing and the campus is expanding to prepare for an increase in the number of students in the coming years. The College is now a part of a growing network of dialogue, support and cooperation that includes institutions both in Europe and the United States, most importantly Bard College in New York, Bennington College in Vermont, and the Bucerius Law School in Hamburg.